ATP-Driven Exchange of Histone H2AZ Variant Catalyzed by SWR1 Chromatin Remodeling Complex
نویسندگان
چکیده
منابع مشابه
ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.
The conserved histone variant H2AZ has an important role in the regulation of gene expression and the establishment of a buffer to the spread of silent heterochromatin. How histone variants such as H2AZ are incorporated into nucleosomes has been obscure. We have found that Swr1, a Swi2/Snf2-related adenosine triphosphatase, is the catalytic core of a multisubunit, histone-variant exchanger that...
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ژورنال
عنوان ژورنال: Science
سال: 2004
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1090701